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    2021-3-28 · Formula : C20H17F2N3O3 · HCl · xH2O Molecular Weight : 421,83 g/mol No components need to be disclosed according to the applicable regulations: Formula: C20H18ClF2N3O3: Molecular Weight (g/mol) 421.83: CAS-No. 91296-87-6: FIRST AID MEASURES: 4.1 Description of first aid measures If inhaled If breathed in, move person into fresh air.

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    2021-4-1 · Sarafloxacin hydrochloride CAS Number: 91296-87-6 Molecular Formula: C20H18ClF2N3O3 Molecular Weight: 421.82 Purity: 98% Certification|Grade: NMR | HPLC Price (, USD): 330/20mg (, USD) Inquiry Synonyms: 6-Fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid hydrochloride Supplier: ALB Technology Limited COA: MSDS: Packaging:

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    Sarafloxacin hydrochloride: Catalog No.: 679803: Relevant identified uses of the substance or mixture: Identified: Laboratory chemical uses: R&D: Uses advised against: HPC Standards GmbH Am Wieseneck 7 04451 Cunnersdorf Deutschland Tel. +49 34291 3372-36 Fax. +49 34291 3372-39 [email protected]: HAZARDS IDENTIFICATION

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    Name: Sarafloxacin HCl CAS#: 91296-87-6 Chemical Formula: C20H18ClF2N3O3 Exact Mass: Molecular Weight: 421.82 Elemental Analysis: C, 56.95; H, 4.30; Cl, 8.40; F, 9.01; N, 9.96; O, 11.38

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  • Sarafloxacin HCl | CAS#91296-87-6 | antibacterial |

    Sarafloxacin HCl is a broad-spectrum fluoroquinolone antibacterial agent. It inhibits bacterial Topo II α (DNA gyrase, topoisomerase) and is effective against Mycobacterium tuberculosis. Product information. CAS Number: 91296-87-6. Molecular Weight: 421.83. Formula: C20H18ClF2N3O3

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  • 3-Quinolinecarboxylicacid, 6-fluoro-1-(4

    Sarafloxacin Hydrochloride: 1.2 Other means of identification. Product number-Other names: 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid,hydrochloride: 1.3 Recommended use of the chemical and restrictions on use. Identified uses: For industry use only. Uses advised against:

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    3-Quinolinecarboxylicacid, 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-,hydrochloride (1:1) Molecular Structure: Formula: C 20 H 17 F 2 N 3 O 3. HCl Molecular Weight: 421.82 Synonyms:

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    2016-1-17 · A heterologous immunoassay has been developed for the determination of sarafloxacin (SRFX) and its analogue residues in milk. A novel hapten with molar mass 499 g was synthesised by introducing a six carbon molecule (6-bromohexanoic acid (BR)) as a spacer arm. This greatly improved the effect of SRFX inducing immune response in mice and enhanced the chance of producing a …

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    2019-7-4 · A nanooptosensor based on the fluorescence quenching of a composite probe was fabricated for the detection of sarafloxacin. The components of the nanocomposite fluorescent probe were a high affinity material of polydopamine polymer (PDA), a selective material of molecularly imprinted polymer (MIP), and optically sensitive quantum dots (QDs).

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    2004-4-1 · The chromatograms obtained from the analysis of milk extracts containing enrofloxacin and ciprofloxacin are shown in Fig. 2 as well as a chromatogram of an extract of control bovine milk. Similar chromatograms of extracts of control bovine plasma and plasma containing enrofloxacin and ciprofloxacin are shown in Fig. 3.No significant interfering peaks were found at the retention times of ...

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  • Determination of sarafloxacin and its analogues in

    2016-1-17 · A heterologous immunoassay has been developed for the determination of sarafloxacin (SRFX) and its analogue residues in milk. A novel hapten with molar mass 499 g was synthesised by introducing a six carbon molecule (6-bromohexanoic acid (BR)) as a spacer arm. This greatly improved the effect of SRFX inducing immune response in mice and enhanced the chance of producing a …

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  • Rapid detection of enrofloxacin using a localized

    2021-4-15 · Due to concerns of antibiotic-resistant bacterial strains from animal-derived food products, different countries or organizations have established their maximum residue limits for antibiotics. Current HPLC and ELISA methods are commonly used in testing antibiotic residues, but have their limitations for in-field rapid detections. Localized surface plasmon resonance (LSPR) sensors have shown ...

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    2016-5-7 · Materials. Six fluoroquinolones, FQs, were used in this work, namely ciprofloxacin hydrochloride (CAS# 86393-32-0), enrofloxacin (CAS# 93107-08-5), moxifloxacin hydrochloride (CAS# 186826-86-8), norfloxacin (CAS# 70458-96-7), ofloxacin (CAS# 82419-36-1) and sarafloxacin (CAS# 91296-87-6) with a quoted purity ≥99 wt% for moxifloxacin hydrochloride, ≥98 wt% for ciprofloxacin hydrochloride ...

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    2020-12-4 · Screening of sarafloxacin, oxolinic acid, and flumequine residues is being developed in finfish at European Union maximum residue limits of 30, 100, and 600 ng/g, respectively, using a portable fluorometer and solid- phase sorbent strips. ... and analyses on different instruments are being compared to achieve the lowest detection limits ...

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  • DETERMINATION OF QUINOLONES IN BOVINE KIDNEY

    2020-9-7 · norfloxacin, nalidixic acid and sarafloxacin) in bovine kidney samples followed by LC-MS/MS analysis. The key parameters of the method were optimized and the method was validated following the 2002/657 EC guidelines. The optimum HF-SLM conditions were therefore; NaH 2 PO 4

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    2018-11-17 · norfloxacin, nalidixic acid and sarafloxacin) in bovine kidney samples followed by LC-MS/MS analysis. The key parameters of the method were optimized and the method was validated following the 2002/657 EC guidelines. The optimum HF-SLM conditions were therefore; NaH 2 PO 4

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    2017-3-1 · The lowest concentration of PEN (0.2 mg/L) gave an SMA of 0.476 g COD-CH 4 /g VSS d and the highest concentration (10.0 mg/L) gave an SMA of 0.101 g COD-CH 4 /g VSS d. In all cases, the initial SMA was 1.192 g COD-CH 4 /g VSS d, which corresponds to the inoculum with the substrate and without the antibiotic.

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    2019-3-25 · The occurrence of pharmaceuticals in the drinking water is a growing concern in China. In this study, we determined the concentration and distribution of 59 selected pharmaceuticals in raw, finished, and tap water samples from 79 drinking water treatment plants (DWTPs) in 15 cities, encompassing seven large river basins in China, using solid-phase extraction pretreatment and ultra …

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    2019-8-6 · sarafloxacin (Vancutsem et al., 1990). Enrofloxacin is closely related to ciprofloxacin, differing only by enrofloxacin's addition of an ethyl group on the piperazinyl ring. In all mammals studied, most enrofloxacin is renally excreted and some is de-ethylated to ciprofloxacin (Brown, 1996; Brown et al., 1990; LeBel, 1988; Neer, 1988; Vancutsem ...

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    Ralf Dohrn is Principal Expert for Properties and Applied Thermodynamics of Bayer AG, Leverkusen, Germany and honorary professor at Technical University Hamburg-Harburg. He studied industrial engineering and received his PhD in chemical engineering. For two years he stayed with Prof. John Prausnitz at the University of California, Berkeley.

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    2007-7-24 · No radioactivity was detected in blood or muscle in fish sampled later than 7d and 14d respectively, Sarafloxacin (C14) Tmax-4 hr 30.4h 42.0h 55.4h 56.3h 12-13 C 3300-4000 g 20 C 52 days old 2 month old 3.0869d 82.8mg/kg for 10d 2.8125d 4.7015d

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    2015-5-18 · been validated for the analysis of three fluoroquinolone antibiotics (ciprofloxacin, enrofloxacin, and sarafloxacin) in beef kidney. Samples were extracted with acidified methanol, centrifuged, diluted with water, and filtered. The diluted extract was analyzed directly by LC/MS (quadrupole) using electrospray ionization (ESI) in positive ion mode.

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    2009-6-6 · Today, high-performance liquid chromatography (HPLC) is the most commonly used methods for screening of FQs residues (Idowu & Peggins, 2004 Idowu, O.R. and Peggins, J.O. 2004. Simple rapid determination of enrofloxacin and ciprofloxacin in bovine milk and plasma by high-performance liquid chromatography with fluorescence detection.

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    2009-3-18 · Abstract An indirect competitive chemiluminescent enzyme-linked immunosorbent assay (CL-ELISA) for detection of gatifloxacin residue in milk was developed in this study. Compared with conventional colorimetric ELISA using the same antibody, the developed CL immunoassay shows a significant improvement in sensitivity and detectability with an IC50 of 0.4 ng mL−1 and a detection …

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    2017-1-27 · The distribution and loss of radioactivity from tissues were determined in 60 juvenile channel catfish (Ictalurus punctatus) following oral dosing with the candidate fish therapeutant Sarafin® ([14C] sarafloxacin hydrochloride) at 10 mg/kg for 5 consecutive days. Twelve groups of 5 fish each were sampled at selected times ranging from 3 to 240 ...

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    2014-3-18 · This results in a reduction in the nutrient cost for maintenance, ... (sarafloxacyne hydrochloride (= sarafloxacin) and enrofloxacyne (= enrofloxacin) (APUA, 2000). ... consumer. The ADI may be set on the basis of toxicological, pharmacological or microbiological data, whichever is the lowest …

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    2019-8-1 · Guanidine hydrochloride Guanidine hydrochloride (special grade) ... Each limit is the lowest of the two or three values obtained using two or three different instruments. ... Chlorhexidine 506 0.01 Sarafloxacin Sarafloxacin 386 0.01 Diaveridin Diaveridin 261 0.02 Diclazuril Diclazuril 275 382 0.01 Dicyclanil Dicyclanil ...

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