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fushuiganshenkang for liver necrosis factories

  • The essential role of CYP2E1 in metabolism and ...

    DMF metabolism as evidenced by increased blood NMHb, and hepatotoxicity as evidenced by elevated liver/body weight ratio, activity of liver enzymes and massive liver necrosis were detected in wild-type (WT) mice but were completely abrogated in KO mice, strongly supporting a CYP2E1-dependent pattern of DMF metabolism and hepatotoxicity.

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  • Mechanisms for virus-induced liver disease: tumor necrosis ...

    1997-12-1 · The contribution of endogenous NK cells and cytokines to virus-induced liver pathology was evaluated during murine cytomegalovirus infections of mice. In immunocompetent C57BL/6 mice, the virus induced a self-limited liver disease characterized by hepatitis, with focal inflammation, and large grossly visible subcapsular necrotic foci.

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  • Extracellular vesicle therapeutics for liver disease ...

    2018-3-10 · d-galactosamine/tumor necrosis factor-α-induced (mouse) Acute: Human or mouse bone marrow MSCs: EVs: Intraperitoneal or intravenous: 2 × 10 8 –2 × 10 10: Reduction of inflammation and apoptosis: Thioacetamide-induced (rat) Chronic: Human embryonic MSCs: EVs: Intrasplenic injection: 350 μgReduction of fibrosis and inflammation

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  • Isolated liver damage in chemical workers.

    Liver biopsies showed severe centrilobular, haemorrhagic liver cell necrosis. The pathological changes resolved within six to 18 months. No damage to other organs was observed. The only worker who resumed work at the plant developed clinical and biochemical evidence of relapse of liver …

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  • The essential role of CYP2E1 in metabolism and ...

    2019-9-9 · For WT mice, necrosis of liver cells was clearly visible, with focal necrosis at 24 h and massive necrosis accompanied by inflammatory cell infiltration at 48 h and 72 h after DMF exposure. Consistent with our previous results, the most serious necrosis of liver cells was observed 48 h after DMF treatment for WT mice.

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  • Liver fibrosis associated with potential vinyl chloride ...

    2020-10-15 · Occupational epidemiological research has revealed that workers exposed to higher VCM in PVC in factories have a higher risk for liver fibrosis (Hsiao et al., 2004; Maroni et al., 2003), and a follow-up study indicated that long-term exposure to VCM and EDC may cause liver disease, liver sclerosis, and hepatomegaly in vinyl chloride workers in Taiwan (Du et al., 1998).

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  • Chronic, Recreational Chloroform-Induced Liver Injury

    2020-7-2 · Abnormal liver function values have previously been detected in humans exposed to DMF, and in some cases, hepatic necrosis/fibrosis was also present. Experimental toxicological studies have also demonstrated DMF-induced liver lesions, which are characterized by necrosis, degeneration, hepatocellular hypertrophy, mitotic figures, and increased serum levels of liver …

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  • The effects of dimethylformamide exposure on liver and ...

    Main Products: 2-Bromo-4-Methylpropiophenone CAS 1451-82 , New BMK CAS 5413-05-8 , Pmk Glycidate CAS 13605-48-6 , BMK Glycidate Powder CAS 16648-44-5 , 2-Bromo-1-Phenyl-1-Pentanone CAS 49851-3. Mgmt. Certification: ISO 9001, GMP. City/Province:

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  • Ammonium glycyrrhizinate Manufacturers & Suppliers,

    Google の無料サービスなら、単語、フレーズ、ウェブページを英語から 100 以上の他言語にすぐに翻訳できます。文字数制限は 5,000 文字です。さらに翻訳するには、矢印を使用してください。

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  • Ammonium glycyrrhizinate Manufacturers & Suppliers,

    ammonium glycyrrhizinate manufacturer/supplier, China ammonium glycyrrhizinate manufacturer & factory list, find qualified Chinese ammonium glycyrrhizinate manufacturers, suppliers, factories, exporters & wholesalers quickly on Made-in-China.com.

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  • The essential role of CYP2E1 in metabolism and ...

    2019-9-9 · N,N-Dimethylformamide (DMF) is a widespread contaminant of leather factories and their surrounding environment. There is a lack of direct in vivo evidence supporting CYP2E1 as a primary enzyme responsible for DMF metabolism and hepatotoxicity. In this study, a novel Cyp2e1 knockout (KO) mouse model was generated and used to assess whether DMF metabolism and …

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  • Mitochondrial MIsCUes in liver regeneration - Guerra ...

    2021-6-3 · A novel biosynthesis of dual reduced graphene oxide/silver nanocomposites (rGO/AgNC) using the crude metabolite of Escherichia coli D8 (MF06257) strain and sunlight is introduced in this work. Physicochemical analysis of these rGO/AgNC revealed that they are sheet-like structures having spherically shaped silver nanoparticles (AgNPs) with an average particle …

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  • In vivo toxicity and antitumor activity of newly green ...

    The ZnO nanoparticles treated fish liver showed some patches of cellular necrosis, changes in sinusoid space, etc., are well-known (Figueiredo-Fernandes et al., 2007; Handy et al., 1999) and often explained by Zn-induced oxidative stress in the liver tissue (Hoyle et al., 2007).

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  • MORPHOLOGICAL AND LIVER HISTOLOGICAL EFFECTS OF

    In 17 cases there was no spread outside the liver. In four cases there had been haemorrhage from oesophageal varices due to non-cirrhotic portal fibrosis diagnosed six to 18 years previously. At necropsy the livers of these men showed considerable, often massive, replacement by tumour, apparently multifocal, with necrosis and haemorrhage.

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  • Occupationally related angiosarcoma of the liver in the ...

    2019-9-9 · N,N-Dimethylformamide (DMF) is a widespread contaminant of leather factories and their surrounding environment. There is a lack of direct in vivo evidence supporting CYP2E1 as a primary enzyme responsible for DMF metabolism and hepatotoxicity. In ...

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  • Hepatoprotective properties of Penthorum chinense Pursh ...

    2017-10-30 · Penthorum chinense Pursh (Penthoraceae, PCP), a well-known Miao ethnomedicine, has been traditionally used to treat several liver-related diseases, such as jaundice and viral hepatitis. The aims of the present study were to evaluate the probable properties of the aqueous extract of PCP on carbon tetrachloride (CCl4)—induced acute liver injury in mice.

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  • Surface components and metabolites of probiotics for ...

    2020-2-5 · The gut microbiota can significantly affect the function of the intestinal barrier. Some intestinal probiotics (such as Lactobacillus, Bifidobacteria, a few Escherichia coli strains, and a new generation of probiotics including Bacteroides thetaiotaomicron and Akkermansia muciniphila) can maintain intestinal epithelial homeostasis and promote health.

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  • Lactic acid bacteria: reviewing the potential of a ...

    2015-9-16 · Lactic acid bacteria (LAB) have a long history of safe exploitation by humans, being used for centuries in food production and preservation and as probiotic agents to promote human health. Interestingly, some species of these Gram-positive bacteria, which are generally recognized as safe organisms by the US Food and Drug Administration (FDA), are able to survive through the …

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  • MORPHOLOGICAL AND LIVER HISTOLOGICAL EFFECTS OF

    The ZnO nanoparticles treated fish liver showed some patches of cellular necrosis, changes in sinusoid space, etc., are well-known (Figueiredo-Fernandes et al., 2007; Handy et al., 1999) and often explained by Zn-induced oxidative stress in the liver tissue (Hoyle et al., 2007).

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  • In vivo toxicity and antitumor activity of newly green ...

    2021-6-3 · A novel biosynthesis of dual reduced graphene oxide/silver nanocomposites (rGO/AgNC) using the crude metabolite of Escherichia coli D8 (MF06257) strain and sunlight is introduced in this work. Physicochemical analysis of these rGO/AgNC revealed that they are sheet-like structures having spherically shaped silver nanoparticles (AgNPs) with an average particle …

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  • Life Science Journal 2012;9(4) http://www.lifesciencesite ...

    2012-10-13 · Histological examination for liver sections revealed marked necrosis and degeneration of hepatocytes, centrilobular necrosis, congestion of the central vein, vacuolization of cytoplasm, ... matters emitted from cement-producing factories also contain high amount of Al which results in environmental pollution (Fatima et al., 2001).

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  • Isolated liver damage in chemical workers

    2019-9-9 · N,N-Dimethylformamide (DMF) is a widespread contaminant of leather factories and their surrounding environment. There is a lack of direct in vivo evidence supporting CYP2E1 as a primary enzyme responsible for DMF metabolism and hepatotoxicity. In ...

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  • Macrophylloflavone: A New Biflavonoid from Garcinia ...

    Isolated liver damagein chemical workers Datafromthree chemicalworkers with liver damage No Age Sex Averagedaily s-ALAT* s-alkaline s-bilirubin Prothrombin Galactose Antipyrine alcohol (IU/I) phosphate (P/noll) ime (arbitrary elimination clearance consumption (normal (IU/I) (normal units) capacity (mmoll (mlln/n)

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  • Occupationally related angiosarcoma of the liver in the ...

    The liver hepatocyte cell damage decreased after giving the compound 1 with various doses (B2, B3, and B4) (Table 4). The compound 1 with dose of 7 μg/kg body weight (B3) and dose of 8 μg/kg body weight (B4) resulted in a number of liver hepatocyte necrosis cells same as the number of normal hepatocyte necrosis cells (A) ().

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  • Cyclophilin A: a key player for human disease | Cell Death ...

    BACKGROUND: Angiosarcoma of the liver (ASL) has been described in vinyl chloride workers worldwide. AIM: To describe the UK experience of occupationally related ASL. PATIENTS: Twenty patients who died from ASL after exposure to vinyl chloride. METHODS: The case records and pathological findings of these 20 patients were reviewed. RESULTS: Twenty men in the United …

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  • Occupationally related angiosarcoma of the liver in the ...

    BACKGROUND: Angiosarcoma of the liver (ASL) has been described in vinyl chloride workers worldwide. AIM: To describe the UK experience of occupationally related ASL. PATIENTS: Twenty patients who died from ASL after exposure to vinyl chloride. METHODS: The case records and pathological findings of these 20 patients were reviewed. RESULTS: Twenty men in the United …

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  • Isolated liver damage in chemical workers

    Isolated liver damagein chemical workers Datafromthree chemicalworkers with liver damage No Age Sex Averagedaily s-ALAT* s-alkaline s-bilirubin Prothrombin Galactose Antipyrine alcohol (IU/I) phosphate (P/noll) ime (arbitrary elimination clearance consumption (normal (IU/I) (normal units) capacity (mmoll (mlln/n)

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  • Substitutes for Bear Bile for the Treatment of Liver ...

    2016-3-3 · Bear bile has been a well-known Chinese medicine for thousands of years. Because of the endangered species protection, the concept on substitutes for bear bile was proposed decades ago. Based on their chemical composition and pharmacologic actions, artificial bear bile, bile from other animals, synthetic compounds, and medicinal plants may be the promising candidates to …

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  • Evidences for lipid involvement in SARS-CoV-2 ...

    2021-3-12 · A striking finding revealed by our study is the presence of numerous lipid droplets induced by SARS-CoV-2 infection, a major difference when compared to SARS-CoV-1 infection. Some (+)RNA viruses ...

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  • Frontiers | Comparative Pathology and Pathogenesis of ...

    2019-9-12 · The study indicates that liver morbidity of birds living in the farms affected by the pollution of brick factories . is higher than the birds living in farms affected by the pollution of oil fields. Keywords: air pollution, apoptosis, carbon nanotube. Introduction. Atmospheric pollutants are the most widespread

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  • Liver diseases in cattle - SlideShare

    2018-12-20 · Tumor necrosis factor ɑ accelerates Hep-2 cells proliferation by suppressing TRPP2 expression 杜鹃 2.78 Sci China Life Sci. 2017 78 Detection of mitochondria membrane potential to study CLIC4 knockdown-induced HN4 cell 沈兵 1.2319 Journal of Visualized 79

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  • Identification of carbon nanotube particles in liver ...

    Cadmium (Cd) is a toxic non-essential transition metal that poses a health risk for both humans and animals. It is naturally occurring in the environment as a pollutant that is derived from agricultural and industrial sources. Exposure to cadmium primarily occurs through the ingestion of contaminated food and water and, to a significant extent, through inhalation and cigarette …

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  • BRITISHA - bmj.com

    In addition to the liver damage Greenburg et al. record more severe pancreatic damagethan in the present case, in which it was confined to minute areas of fat necrosis. These changes are thought to result from the liver necrosis and not from the effects of the toxic agent. Theretroperitoneal oedema found was probably the result of giving ...

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  • Grand Rounds: An Outbreak of Toxic Hepatitis among ...

    2007-1-1 · A study on the prevalence and risk factors of liver dysfunction among the workers in chemical factories [in Korean]. Korean J Prev Med 30:103-112. Google Scholar; Chitturi S, Farrell GC. 2000. Herbal hepatotoxicity: an expanding but poorly defined problem. J Gastroenterol Hepatol 15:1093-1099 11106086. Crossref, Medline, Google Scholar

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  • The effects of size and surface modification of amorphous ...

    2015-4-2 · In experiment 1, liver sections from the SP30, 70, and 300-NH 2 or –COOH-treated mice had almost normal histological patterns (figure 4(a)), suggesting amino or carboxyl surface modification mitigated the liver toxicity of SP30, 70, or 300-plain as these SP-plain all induced hepatocytic degenerative necrosis in the liver .

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  • Phosphorus - National Center for Homeopathy

    Liver, diseases of, acute yellow atrophy of. Locomotor ataxy. Lumps, hemorrhage from, oedema of, paralysis of. ... and the effects on workers in match factories, especially necrosis of the lower jaw. ... Langenbeck objects to the term 'necrosis,’ stating that it is a periostatics in which bony deposit occurs, enclosing the jaws more or less ...

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  • Cyclophilin A: a key player for human disease | Cell Death ...

    2020-7-20 · Background Plant-derived extracellular vesicles (PDEVs) have great potential for clinical applications. Ultracentrifugation, considered the gold standard method for the preparation of PDEVs, is efficacious but time-consuming and highly instrument-dependent. Thus, a rapid and handy method is needed to facilitate the basic researches and clinical applications of PDEVs. …

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  • An efficient method to isolate lemon derived extracellular ...

    Like most DNA viruses, herpesviruses precisely deliver their genomes into the sophisticatedly organized nuclei of the infected host cells to initiate subsequent transcription and replication. However, it remains elusive how the viral genome specifically interacts with the host genome and hijacks host transcription machinery. Using pseudorabies virus (PRV) as model virus, we …

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  • Liver-directed lentiviral gene therapy in a dog model of ...

    We are an Open Access publisher and international conference Organizer. We own and operate 500 peer-reviewed clinical, medical, life sciences, engineering, and management journals and hosts 3000 scholarly conferences per year in the fields of clinical, medical, pharmaceutical, life sciences, business, engineering and technology.

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  • RUNX1-mediated alphaherpesvirus-host trans-species ...

    2020-9-23 · Leist et al. present a mouse model for COVID-19 by serially passaging human SARS-CoV-2 in vivo to create an evolution-selected lethal mouse-adapted virus variant, called MA10. MA10 shows a dose- and age-related increase in pathogenesis in standard laboratory mice and recapitulates key features of COVID-19 in humans.

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  • Grand Rounds: An Outbreak of Toxic Hepatitis among ...

    2007-1-1 · A study on the prevalence and risk factors of liver dysfunction among the workers in chemical factories [in Korean]. Korean J Prev Med 30:103-112. Google Scholar; Chitturi S, Farrell GC. 2000. Herbal hepatotoxicity: an expanding but poorly defined problem. J Gastroenterol Hepatol 15:1093-1099 11106086. Crossref, Medline, Google Scholar

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  • Liver-directed lentiviral gene therapy in a dog model of ...

    In addition to the liver damage Greenburg et al. record more severe pancreatic damagethan in the present case, in which it was confined to minute areas of fat necrosis. These changes are thought to result from the liver necrosis and not from the effects of the toxic agent. Theretroperitoneal oedema found was probably the result of giving ...

    Get Price
  • BRITISHA - bmj.com

    Liver, diseases of, acute yellow atrophy of. Locomotor ataxy. Lumps, hemorrhage from, oedema of, paralysis of. ... and the effects on workers in match factories, especially necrosis of the lower jaw. ... Langenbeck objects to the term 'necrosis,’ stating that it is a periostatics in which bony deposit occurs, enclosing the jaws more or less ...

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  • Phosphorus - National Center for Homeopathy

    2020-8-29 · by activated inflammatory factories not by the damaging agent.[5] ... swelling, necrosis with infiltration of heterophiles and lymphocytes were observed microscopically in the examined organs. PCR technique was positive for Duck viral hepatitis and it was the best tool to diagnose the disease. ... ( The liver showing congestion of hepatic ...

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  • Functional Foods for the Management of Non-Alcoholic

    2021-6-25 · SOUTH SAN FRANCISCO, Calif., June 25, 2021 (GLOBE NEWSWIRE) -- Surrozen Inc., a biotechnology company discovering and developing drug candidates to selectively modulate the Wnt pathway, announced today that data from preclinical studies of SZN-043 were presented during The Digital International Liver Congress™ 2021 (ILC), the Annual Meeting of the European …

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  • PATHOLOGICAL AND MOLECULAR INVESTIGATION OF

    ASFV p54 antibody detects envelope protein p54 of African swine fever virus. Protein p54, encoded by the E183L gene, is a 20 kDa type I transmembrane protein that localizes to envelope precursors derived from the host ER. p54 is involved in intracellular microtubule-dependent transport of viral capsid toward viral factories, and is detected on membrane-like structures within viral factories ...

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  • Surrozen Presents Data at 2021 International Liver ...

    2013-1-22 · pounds. Aflatoxins B2 and G2 were established as the dihydroxy derivatives of B1 and G1, respectively. Whereas, aflatoxin M1 is 4-hydroxy aflatoxin B1 and aflatoxin M2 is 4-dihy‐ droxy aflatoxin B2.Of the four major aflatoxins (B1, B2, G1 and G2), G2 occurs in high quanti‐ ties though less toxic while AFB1 is the most toxic of all the aflatoxin. The World Health

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  • Anti-ASFV p54 antibody [GT853] (GTX635690) | GeneTex

    Like most DNA viruses, herpesviruses precisely deliver their genomes into the sophisticatedly organized nuclei of the infected host cells to initiate subsequent transcription and replication. However, it remains elusive how the viral genome specifically interacts with the host genome and hijacks host transcription machinery. Using pseudorabies virus (PRV) as model virus, we …

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  • Mitochondria as biosynthetic factories for cancer ...

    2015-1-25 · Unchecked growth and proliferation is a hallmark of cancer, and numerous oncogenic mutations reprogram cellular metabolism to fuel these processes. As a central metabolic organelle, mitochondria execute critical biochemical functions for the synthesis of fundamental cellular components, including fatty acids, amino acids, and nucleotides.

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  • Shattering barriers toward clinically meaningful MSC ...

    » A complete version of the work and all supplemental materials, including a copy of the permission as stated above, in a suitable standard electronic format is deposited immediately upon initial publication in at least one online repository that is supported by an academic institution, scholarly society, government agency, or other well-established organization that seeks to enable Open ...

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  • Open Access | Open Access Publications - Open Access

    If enough glomeruli are damaged, kidney function is decreased. As a result, urine production falls and waste products build up in the blood. Also, when damage is severe, inflammatory cells and injured glomerular cells accumulate, compressing the …

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  • Recent Advances in Microalgal Bioactives for Food, Feed ...

    2021-7-6 · Hypertrophy definition: enlargement of an organ or part resulting from an increase in the size of the cells | Meaning, pronunciation, translations and examples

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  • Kiem Saphia - 1st World Herbal Alkali Pharmaceutical ...

    Alkaline for Kidney and Liver. Supports liver toxicity, restores damaged liver cells & kidneys, liver cirrhosis, improves liver and kidney function, improves health and physical strength, ceases fatigue. Reduces nightime urination, dysuria, reduces itching rashes, cramps of limbs, restores injured cells, functions of the kidney & liver

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  • Rotavirus outsources cellular protein to assemble virus ...

    2018-12-4 · Rotavirus outsources cellular protein to assemble virus factories. Dipali Pathak. 713-798-4710. Houston, TX - Dec 4, 2018. Media Component. Content. Rotaviruses, like all viruses, reproduce inside living cells. Making new viruses requires assembling replication factories via a complex, little known process that involves both viral and cellular ...

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  • Mitochondria as biosynthetic factories for cancer ...

    2015-1-25 · Unchecked growth and proliferation is a hallmark of cancer, and numerous oncogenic mutations reprogram cellular metabolism to fuel these processes. As a central metabolic organelle, mitochondria execute critical biochemical functions for the synthesis of fundamental cellular components, including fatty acids, amino acids, and nucleotides.

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  • Shattering barriers toward clinically meaningful MSC ...

    More than 1050 clinical trials are registered at [FDA.gov][1] that explore multipotent mesenchymal stromal cells (MSCs) for nearly every clinical application imaginable, including neurodegenerative and cardiac disorders, perianal fistulas, graft-versus-host disease, COVID-19, and cancer. Several companies have or are in the process of commercializing MSC-based therapies. However, most …

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  • Streptococcus thermophilus alters the expression of genes ...

    2020-2-11 · Consumption of probiotics contributes to a healthy microbiome of the GIT leading to many health benefits. They also contribute to the modulation of the immune system and are becoming popular for the treatment of a number of immune and inflammatory diseases. The main objective of this study was to evaluate anti-inflammatory and modulatory properties of …

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  • Perforin-2 is essential for intracellular defense of ...

    2015-9-24 · An effective defense against foreign invaders is fundamental to an organism's survival. It is likely that immunity began to develop shortly after the emergence of Earth's first single-celled organisms and a remnant of that distant past still exists in our present day immune system in the form of Perforin-2. This ancient protein has been highly conserved throughout evolution from …

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  • Overview of Kidney Filtering Disorders - Kidney and ...

    If enough glomeruli are damaged, kidney function is decreased. As a result, urine production falls and waste products build up in the blood. Also, when damage is severe, inflammatory cells and injured glomerular cells accumulate, compressing the …

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  • Immune-Mediated Skin Disorders of Dogs | Today's ...

    2021-7-3 · Systemic lupus affects multiple organs, including the skin for 40% to 50% of affected dogs. Systemic lupus is characterized by production of a variety of autoantibodies that form circulating immune complexes ( FIGURE 10 ). These complexes can become “stuck” in different parts of the body, including organs.

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  • anti-dsRNA mAb J2 | SCICONS 10010500 product

    2018-9-12 · Hepatitis C virus double-stranded RNA is the predominant form in human liver and in interferon-treated cells. Hepatology. 2017;66:357-370 pubmed publisher Wang H, Tai A. Continuous de novo generation of spatially segregated hepatitis C virus replication organelles revealed by pulse-chase imaging.

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  • 3. HEALTH EFFECTS

    2013-4-18 · Hepatic 60 250 (increased liver weight and centrilobular hepatocyte necrosis) Resp 80 M (single cell necrosis in nasal olfactory epithelium) Cruzan et al. 2001 Styrene Resp 40 M 160 M (moderate to marked degenerative changes in olfactory epithelium) Green et al. 2001a Styrene Hepatic 125 250 M (pigmented macrophages and focal necrosis)

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  • The Risk Assessment Information System

    Liver: Hepatomegaly and cirrhosis of the liver were reported in children exposed to high levels of copper in drinking water. Cirrhosis of the liver may occur in patients with Wilson's disease. Hepatic effects observed in animals include increased copper deposition, necrosis, inflammation, and increased ALT and AST levels.

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  • (PDF) Bioaccumulation of Some Heavy Metals and ...

    The high degeneration and lymphocytic infiltration and accumulation of zinc in studied fish liver agrees with hepatocellular focal necrosis (Figs. 30, 32-40). In addition Hamed [26]. Ibrahim and Mahmoud [24] revealed that this to the above, a noticeable damage to pancreatic cells was increase is anticipated to industrial effluents from Talkha ...

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  • Bioprocessing strategies for the large-scale production of ...

    2015-11-23 · Human mesenchymal stem cells (hMSCs), also called mesenchymal stromal cells, have been of great interest in regenerative medicine applications because of not only their differentiation potential but also their ability to secrete bioactive factors that can modulate the immune system and promote tissue repair. This potential has initiated many early-phase clinical studies for the …

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  • Regenerative medicine: Current therapies and future ...

    » A complete version of the work and all supplemental materials, including a copy of the permission as stated above, in a suitable standard electronic format is deposited immediately upon initial publication in at least one online repository that is supported by an academic institution, scholarly society, government agency, or other well-established organization that seeks to enable Open ...

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  • Open Access | Open Access Publications - Open Access

    Recent advancements in cancer biology, microbiology, and bioengineering have spurred the development of engineered live biotherapeutics for targeted cancer therapy. In particular, natural tumor-targeting and probiotic bacteria have been engineered for controlled and sustained delivery of anticancer agents into the tumor microenvironment (TME). Here, we review the latest …

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  • The Use of Biosensors for Biomonitoring Environmental ...

    2020-5-2 · The first Industrial Revolution began in Great Britain after 1750. Britain had financial institutions in place, such as a central bank, to finance new factories. The profits Britain had enjoyed due to booming cotton and trade industries allowed investors to support the construction of factories.

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  • S-adenosylmethionine in Liver Health, Injury, and Cancer ...

    2012-10-1 · S-adenosylmethionine (AdoMet, also known as SAM and SAMe) is the principal biological methyl donor synthesized in all mammalian cells but most abundantly in the liver.Biosynthesis of AdoMet requires the enzyme methionine adenosyltransferase (MAT). In mammals, two genes, MAT1A that is largely expressed by normal liver and MAT2A that is …

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  • 3. HEALTH EFFECTS

    2013-4-18 · Hepatic 60 250 (increased liver weight and centrilobular hepatocyte necrosis) Resp 80 M (single cell necrosis in nasal olfactory epithelium) Cruzan et al. 2001 Styrene Resp 40 M 160 M (moderate to marked degenerative changes in olfactory epithelium) Green et al. 2001a Styrene Hepatic 125 250 M (pigmented macrophages and focal necrosis)

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  • 2. RELEVANCE TO PUBLIC HEALTH - Centers for Disease ...

    2011-10-21 · cirrhosis of the liver, acute liver failure, and congenital deficiencies of any of the urea cycle enzymes. Liver disease can result in decreased metabolism of ammonia with resultant increased levels of ammonia in the bloodstream and in the brain, which can produce neurological effects such as seizures and coma, and eventually death.

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  • Function and dysfunction of plasma cells in intestine ...

    The high degeneration and lymphocytic infiltration and accumulation of zinc in studied fish liver agrees with hepatocellular focal necrosis (Figs. 30, 32-40). In addition Hamed [26]. Ibrahim and Mahmoud [24] revealed that this to the above, a noticeable damage to pancreatic cells was increase is anticipated to industrial effluents from Talkha ...

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  • (PDF) Bioaccumulation of Some Heavy Metals and ...

    2008-8-19 · Human Fas Ligand (hFasL) is a 37-kDa glycoprotein that belongs to the tumor necrosis factor family and plays important roles in cancer and autoimmune diseases. The hFasL was successfully produced as a bioactive form in Dd ( 92 , 93 ) and purified using single-step Ni-affinity chromatography with a recovery of 92% and purity of 91%, respectively ...

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  • Dictyostelium discoideum—a promising expression system

    2015-11-23 · Human mesenchymal stem cells (hMSCs), also called mesenchymal stromal cells, have been of great interest in regenerative medicine applications because of not only their differentiation potential but also their ability to secrete bioactive factors that can modulate the immune system and promote tissue repair. This potential has initiated many early-phase clinical studies for the …

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  • Bioprocessing strategies for the large-scale production of ...

    2015-1-22 · Satellites are subviral agents that differ from viroids because they depend on the presence of a helper virus for their propagation. Satellite viruses are particles that contain nucleic acid genomes encoding a structural protein that encapsidates the satellite genome.Satellite RNAs do not encode capsid protein, but are packaged by a protein encoded in the helper virus genome.

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  • Satellites – the viral kind - virology

    Cadmium (Cd), lead (Pb) and to a lesser extent mercury (Hg) are widespread occupational and environmental toxins. Human exposure can occur due to activities such as mining, melting, soldering, welding, plating, recycling of metals, fossil fuel combustion and industrial applications [ …

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