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a new synergized glutaraldehyde-phenate

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    Research leading to the development of Sporicidin, a new (synergized glutaraldehyde-phenate) sterilant and concentrated disinfectant, is reported. Microbial evaluation and shelf life testing of the new formulation was done using AOAC tests--Use-Dilution, Sporicidal, Tuberculocidal--and …

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    An Efficacy Evaluation of a Synergized Glutaraldehyde-Phenate Solution in Disinfecting Respiratory Therapy Equipment Contaminated During Patient Use - Volume 3 Issue 3

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    An efficacy evaluation of a synergized glutaraldehyde-phenate solution in disinfecting respiratory therapy equipment contaminated during patient use. T. R. Townsend, S. B. Wee, B. Koblin School of Medicine

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    1994-11-1 · A new synergized glutaraldehyde-phenate sterilizing solution and concentrated disinfectant. Leach ED. Infect Control, 2(1):26-30, 01 Jan 1981 Cited by: 10 articles | PMID: 6783583

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    Reusable, corrugated, expiratory limb ventilator tubing that had been in use for 24 hours, were randomly allocated to one of three groups: no treatment (N = 36); detergent wash (N = 83); or a detergent wash followed by a 10 minute immersion in a 1:16 dilution of synergized glutaraldehyde-phenate solution which was reused for 30 days.

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    1988-5-1 · A new synergized glutaraldehyde-phenate sterilizing solution and concentrated disinfectant Infect Control , 2 ( 1981 ) , pp. 26 - 30 View Record in Scopus Google Scholar

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    1994-12-1 · We evaluated the efficacy of phenolated glutaraldehyde in a 1:8 solution for the disinfection of bronchofibroscopes that were highly contaminated with Serratia marcescens and Pseudomona aeruginosa. An Olympus BF-P10 bronchofibroscope was contaminated with artificial samples containing one of the aforementioned microorganisms in concentrations nearing 10 8 colony forming units per …

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    Fixed walls: Journals with no new volumes being added to the archive. Absorbed: Journals that are combined with another title. Complete: Journals that are no longer published or …

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    This article reviews parameters which must be considered in the selection of heat sterilization techniques (autoclave, chemiclave, or dry heat) and also chemicals for disinfection and sterilization (2 per cent glutaraldehyde, quaternary ammonium compounds, iodophors, alcohol, sodium hypochlorite, and synthetic phenols).

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    A new synergized glutaraldehyde-phenate sterilizing solution and concentrated disinfectant. Leach ED. Infect Control, (1):26-30 1981 MED: 6783583 10. Anonymous. Research Department, Dental Products Report. Dental asepsis survey. Dent Prod Rep 1984;June:27. Show 4 more references (10 of 14) Citations & impact . Impact metrics ...

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  • An efficacy evaluation of a synergized glutaraldehyde ...

    Reusable, corrugated, expiratory limb ventilator tubing that had been in use for 24 hours, were randomly allocated to one of three groups: no treatment (N = 36); detergent wash (N = 83); or a detergent wash followed by a 10 minute immersion in a 1:16 dilution of synergized glutaraldehyde-phenate solution which was reused for 30 days.

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    1996-4-1 · A new synergized glutaraldehyde-phenate sterilizing solution and concentrated disinfectant. Infect Control, 2 (1981), pp. 3-6. View Record in Scopus Google Scholar. 22. A Dyas, BC Das. The activity of glutaraldehyde against Clostridium difficile. J Hosp Infect, 6 (1985), pp. 41-45.

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    1984-9-1 · A new synergized glutaraldehyde-phenate sterilizing solution and concentrated disinfectant. Infect Control, 2 (1981), pp. 26-30. View Record in Scopus Google Scholar. 14. AA Fisher. Reactions to glutaraldehyde with particular reference to radiologists and x …

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    Leach ED. A new synergized glutaraldehyde-phenate sterilizing solution and concentrated disinfectant. Infect Control. 1981 Jan-Feb; 2 (1):26–30. Rutala WA. APIC guideline for selection and use of disinfectants. Am J Infect Control. 1990 Apr; 18 (2):99–117. Rutala WA, Cole EC.

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    1988-5-1 · A new synergized glutaraldehyde-phenate sterilizing solution and concentrated disinfectant. Infect Control, 2 (1981), pp. 26-30. View Record in Scopus Google Scholar. 14. GF Mallison, PG Standard. Safe storage times for sterile packs. Hospitals, 48 (1974), pp. 77-80. View Record in Scopus Google Scholar. 15.

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    1994-12-1 · A new synergized glutaraldehyde-phenate sterilizing solution and concentrated disinfectant. Infect Control, 2 (1981), pp. 26-30. View Record in Scopus Google Scholar. 5. G. Rodríguez-Froján, J. Castella, V. Ausina, C. Puzo. Estudio experimental de la desinfección del broncofibroscopio.

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  • [PDF] SPORICIDAL ACTIVITY OF ALKALINE

    During a search for a sporicidal agent to equal or surpass formaldehyde in activity, a group of saturated dialdehydes ranging from two to six carbons was discovered. These dialdehydes exerted a surprisingly high degree of activity in isopropanol buffered with a carbonate or bicarbonate. Without the proper buffer, practically no activity was observed. A solution of 1% glutaraldehyde, 0.3% NaHCO ...

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    2020-8-20 · A new synergized glutaraldehyde-phenate sterilizing solution and concentrated disinfectant. American Academy of Ophthalmology. Transmission of viruses via contact in a household setting: Killing activity of microwaves in milk. Transmission of HIV in dialysis centre.

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    A new synergized glutaraldehyde-phenate sterilizing solution and concentrated disinfectant. Infect Control, 2 (1981), pp. 26-30. Medline ... Evaluation of a glutaraldehyde-phenate solution used to disinfect endoscopes and instruments in a freestanding surgical facility. J …

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    1984-9-1 · A new synergized glutaraldehyde-phenate sterilizing solution and concentrated disinfectant. Infect Control, 2 (1981), pp. 26-30. View Record in Scopus Google Scholar. 14. AA Fisher. Reactions to glutaraldehyde with particular reference to radiologists and x …

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  • Method and device for disinfecting biological fluids

    Leach, 'A New Synergizer Glutaraldehyde-Phenate Sterilizing Solution and Concentrated Disinfectant,' Infection Control 2, 1981, pp. 3-6. Leach, 'Repeated Insult Patch Testing of Sporcidin Diluted 1:16 With 15 Parts Water,' Laboratory Results from Milligan College, 3/09/84.

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  • Glutaraldehyde - Zxchem Group - China Manufactory

    Glutaraldehyde CasNo.: 111-30-8 is a liquid chemical with many advantages like a disinfectant preservative and fixing agent. It is an efficient agent for a range of microorganisms including spores. Glutaraldehyde is a chemical that belongs to the dialdehyde group that has reached wide application as an advanced disinfection agent and sterilant chemical.

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    Novel glutaraldehyde formulations (e.g., glutaraldehyde-phenol-sodium phenate, potentiated acid glutaraldehyde, stabilized alkaline glutaraldehyde) produced in the past 30 years have overcome the problem of rapid loss of activity (e.g., use-life 28–30 days) while generally maintaining excellent microbicidal activity.

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  • FDA-Cleared Sterilants and High Level Disinfectants

    2019-9-25 · 1.12% glutaraldehyde 1.93% phenol/phenate: Indication for device sterilization. 12 hrs at 25°C 14 days Maximum Reuse Contact conditions based on AOAC Sporicidal Activity Test only.

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    A room temperature aqueous sterilizing composition comprising from 0.75 -4.0% by wt. of glutaraldehyde and from 4-15% by wt of phenol and a metal phenate, preferably sodium phenate.Optionally present are 1-5% by wt of sodium tetraborate, 2-10% by wt of a humectant such as glycerol, di-ethylene glycol or propylene glycol, and a surfactant. A preferred pH range is pH 7.0 - 7.4.

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  • US Patent for Buffered phenol-glutaraldehyde

    2017-10-17 · New Products and Processes* zNew high-level disinfectants (HLD) Superoxidized water zNew chemical sterilants/HLD 3.4% glutaraldehyde with 26% isopropanol 8.3% hydrogen peroxide with 7.0% peracetic acid zNew sterilization process Ozone *Limited data in the scientific literature that assesses the antimicrobial activity or material compatibility

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  • Disinfection and Sterilization

    2017-10-17 · Disinfection and Sterilization in Healthcare Facilities WA Rutala, DJ Weber, and HICPAC, “In press” zOverview Last Centers for Disease Control and Prevention guideline in 1985 274 pages (>130 pages preamble, 21 pages recommendations, glossary of terms, tables/figures, >1100 references)

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  • Disinfection and Sterilization

    2000-9-1 · Glutaraldehyde is considered the disinfectant of choice for sterilizing medical and dental equipment. Unfortunately, glutaraldehyde has many toxic side‐effects, including the ability to induce allergic contact dermatitis. In a 5‐year study at the University of Kansas, 468 patients were patch tested to glutaraldehyde. A comparison of results was made between those employed in a health ...

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    2017-7-26 · What’s New. www.disinfectionandsterilization.org • Current Issues and New Technologies Sterilization of critical items Biological indicators, modified Spaulding, extended claims High-level disinfection for semi-critical items Endoscope reprocessing issues (duodenoscopes), HPV risks/studies Low-level disinfection of noncritical items-

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    2019-12-4 · Glutaraldehyde, concentrations and conditions for HLD, according to FDA Glutaraldehyde Contact conditions 1,12% glutaraldehyde, 1.93% phenol-phenate 25° C , 20 min 2,4 a 2,6% glutaraldehyde without surfactants 20-25° C , 45 min 2,4 a 2,5% glutaraldehyde with ... new …

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    2020-12-21 · A new synergized glutaraldehyde-phenate sterilizing answer and concentrated disinfectant. Comparison of two activated glutaraldehyde solutions: Cidex Solution and Sonacide. Last replace: May 2019 146 of 163 Guideline for Disinfection and Sterilization in Healthcare Facilities, 2008 Philadelphia: Lea & Febiger, 1991:596-616.

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  • Find Research outputs — Johns Hopkins University

    An efficacy evaluation of a synergized glutaraldehyde-phenate solution in disinfecting respiratory therapy equipment contaminated during patient use.

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  • The safety of reused endotracheal tubes sterilized ...

    2007-8-1 · An efficacy evaluation of a synergized glutaraldehyde-phenate solution in disinfecting respiratory therapy equipment during patient use Infect Control , 3 ( 1982 ) , pp. 240 - 244 View Record in Scopus Google Scholar

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    Glutaraldehyde: a new fixative in endodontics. J Dent Res 1973; 52(3):601 (abstract nº 48). [ Links ] 35. Leach ed. A new synergized glutaraldehyde-phenate sterilizing solution and concentrated desinfectant. Infect Control 1981;2(1):26-30. [ Links ] 36. Tsai t-p, su h-l, Tseng l-h. Glutaraldehyde preparations and pulpotomy in primary molars.

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    Evaluation of the efficacy of glutaraldehyde and peroxygen for disinfection of dental instruments I.F. Angelillo, A. Bianco, C.G.A. Nobile and M. Pavia Medical School, University of Catanzaro, Italy 1752/98: received 16 July 1998 and accepted 23 July 1998 I.F. ANGELILLO, A. BIANCO, C.G.A. NOBILE AND M. PAVIA. 1998. The antimicrobial and

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    Después de analizar los estudios clínicos de las técnicas de pulpotomía en dientes temporales alternativas al formocresol: hidróxido de calcio, electrocoagulación, glutaraldehido,

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    An efficacy evaluation of a synergized glutaraldehyde-phenate solution in disinfecting respiratory therapy equipment contaminated during patient use. Infect. Control 1982;3:240-4. Petersen NJ, Carson LA, Doto IL, Aguero SM, Favero MS. Microbiologic evaluation of a new glutaraldehyde-based disinfectant for hemodialysis systems. Trans. Am. Soc ...

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    2007-8-1 · An efficacy evaluation of a synergized glutaraldehyde-phenate solution in disinfecting respiratory therapy equipment contaminated during patient use. Townsend TR, Wee SB, Koblin B. Infect Control, (3):240-244 MED: 6807934

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    Allergic contact dermatitis of the hands from Sporicidin (glutaraldehyde-phenate) used to disinfect endoscopes. Fisher AA(1). Author information: (1)New York University Medical School. PMID: 2109674 [Indexed for MEDLINE] MeSH terms. Aldehydes/adverse effects* Dermatitis, Contact/etiology* Endoscopes; Glutaral/adverse effects*

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    2021-5-1 · An effective method for the assignment of 31 P‐nmr resonance(s) of oligonucleotides Cheng, D. M., Kan, LS. S., Miller, P. S., Leutzinger, E. E. & Ts'o, P. O. P ...

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  • Análisis de los estudios clínicos sobre la eficacia de las ...

    Glutaraldehyde: a new fixative in endodontics. J Dent Res 1973; 52(3):601 (abstract nº 48). [ Links ] 35. Leach ed. A new synergized glutaraldehyde-phenate sterilizing solution and concentrated desinfectant. Infect Control 1981;2(1):26-30. [ Links ] 36. Tsai t-p, su h-l, Tseng l-h. Glutaraldehyde preparations and pulpotomy in primary molars.

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    1988-4-1 · Journal of Hospital Infection (1988) 11, 278-285 Evaluation of three disinfectants after in-use stress Henry D. Isenberg, Edmund R. Giugliano, Kenneth France and Phyllis Alperstein Long Island Jewish Medical Center, New Hyde Park, NY 11042 and Health Science Center, State University at Stony Brook, Stony Brook, NY 117-94 Accepted for publication 28 July 1987 Summary: Solutions of 2-0% …

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    1. GALAMBOS J.T. — Transmission of Hepatitis B from Providers to Patients: How Big is the Risk?Hepatology, 1986, 6, 320–325.. PubMed Article CAS Google Scholar . 2. HUGHES C.E., GEBHARD R.L., PETERSON L.R., GERDING D.N. — Efficacy of routine fiberoptic endoscope cleaning and disinfection for killing Clostridium difficile.

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    An efficacy evaluation of a synergized glutaraldehyde-phenate solution in disinfecting respiratory therapy equipment contaminated during patient use. Infect. Control 1982;3:240-4. Petersen NJ, Carson LA, Doto IL, Aguero SM, Favero MS. Microbiologic evaluation of a new glutaraldehyde-based disinfectant for hemodialysis systems. Trans. Am. Soc ...

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  • Glutaraldehyde - Zxchem Group - China Manufactory

    Glutaraldehyde CasNo.: 111-30-8 is a liquid chemical with many advantages like a disinfectant preservative and fixing agent. It is an efficient agent for a range of microorganisms including spores. Glutaraldehyde is a chemical that belongs to the dialdehyde group that has reached wide application as an advanced disinfection agent and sterilant chemical.

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    Glutaraldehyde: a new fixative in endodontics. J Dent Res 1973; 52(3):601 (abstract nº 48). [ Links ] 35. Leach ed. A new synergized glutaraldehyde-phenate sterilizing solution and concentrated desinfectant. Infect Control 1981;2(1):26-30. [ Links ] 36. Tsai t-p, su h-l, Tseng l-h. Glutaraldehyde preparations and pulpotomy in primary molars.

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    Author information: (1)Long Island Jewish Medical Center, New Hyde Park, NY 11042. Solutions of 2.0% and 3.4% glutaraldehyde, and of 0.5% phenate with 0.18% glutaraldehyde were stressed with a microbial and organic soil load for the periods advocated by the respective manufacturers.

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    A room temperature aqueous sterilizing composition comprising from 0.75 -4.0% by wt. of glutaraldehyde and from 4-15% by wt of phenol and a metal phenate, preferably sodium phenate. Optionally present are 1-5% by wt of sodium tetraborate, 2-10% by wt of a humectant such as glycerol, di-ethylene glycol or propylene glycol, and a surfactant.

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    2008-10-9 · Asporin (Farmec, Verona, Italy) is an aqueous solution of 2% glutaraldehyde activated by the addition of sodium phenate solution (final pH 7·9–8·0) at the time of testing. Virkon (Antec International, Sudbury, UK) is a balanced, stabilized blend of peroxygen compounds, surfactant, organic acids and an inorganic buffer system containing ...

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    2020-3-11 · New Formulation Changes ... [six facilities using 1:16 glutaraldehyde phenate], is not FDA-cleared as a high-level disinfectant [an iodophor] or no disinfecting agent) and before use on the next patient129. The incidence of postendoscopic procedure infections from an improperly processed endoscope has not been rigorously assessed.

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    2014-7-18 · Novel glutaraldehyde formulations (e.g., glutaraldehyde-phenol-sodium phenate, potentiated acid glutaraldehyde, stabilized alkaline glutaraldehyde) produced in the past 30 years have overcome the problem of rapid loss of activity (e.g., use-life 2830 days) while generally maintaining excellent 584-588 .

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    2017-9-27 · Appendix A—Guide to Sterilization and Disinfection of Instruments, Equipment Surfaces Scrub items with friction to remove all visible soiling before disinfecting or sterilizing. Do NOT use hand sanitizers or antiseptic hand soap to clean equipment and surfaces.

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    Current Issues and New Technologies Spaulding classification Recommended sterilants and disinfectants, CDC/HICPAC Critical devices Semicritical device Non-critical devices Endoscopes continue to be the highest risk devices used in hospitals New guidelines for cleaning and disinfection Improving room cleaning and disinfection

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    2019-12-4 · Glutaraldehyde, concentrations and conditions for HLD, according to FDA Glutaraldehyde Contact conditions 1,12% glutaraldehyde, 1.93% phenol-phenate 25° C , 20 min 2,4 a 2,6% glutaraldehyde without surfactants 20-25° C , 45 min 2,4 a 2,5% glutaraldehyde with ... new …

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    2017-6-27 · Although oncolytic therapy is showing great potential in clinical trials, not all patients benefit from it. Combining oncolytic viruses with anticancer chemicals could provide a better chance to increase the response rate. Here, we report that the combination of an alphavirus (M1) that we identified previously and second mitochondria-derived activator of caspases (Smac) mimetic compounds (SMCs ...

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    2017-11-14 · .14 1,5 Pentanediol solution, (5-50%) (Glutaraldehyde solutions (50% or less)) EHS 1107 .15 Urea/Ammonium nitrate solution EHS 1387 4.4 The group also noted that a number of substances had been carried over from either past sessions of the ESPH Working Group, based on …

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    2000-7-18 · Glutaraldehyde is a colorless liquid with a pungent odor used to disinfect medical and dental equipment. It is also used for industrial water treatment and as a chemical preservative.; Glutaraldehyde is an oily liquid at room temperature (density 1.06 g/mL), and miscible with water, alcohol, and benzene.

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    Letters in Applied Microbiology 1998, 27, 292–296 Evaluation of the efficacy of glutaraldehyde and peroxygen for disinfection of dental instruments I.F. Angelillo, A. Bianco, C.G.A. Nobile and M. Pavia Medical School, University of Catanzaro, Italy 1752/98: received 16 July 1998 and accepted 23 July 1998 The antimicrobial and I .F .

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    2019-9-25 · 1.12% glutaraldehyde 1.93% phenol/phenate: Indication for device sterilization. 12 hrs at 25°C 14 days Maximum Reuse Contact conditions based on AOAC Sporicidal Activity Test only.

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    A 2.0% glutaraldehyde–7.05% phenol–1.20% sodium phenate product that contained 0.125% glutaraldehyde–0.44% phenol–0.075% sodium phenate when diluted 1:16 is not recommended as a high-level disinfectant because it lacks bactericidal activity in the presence of organic matter and lacks tuberculocidal, fungicidal, virucidal, and sporicidal ...

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    2017-10-17 · Cidex, 2.4% glutaraldehyde Cidex-OPA, 0.55% OPA Wavicide, 2.65% glutaraldehyde Aldahol, 3.4% glutaraldehyde and 26% alcohol Control Measures C. difficile zHandwashing (soap and water) , contact precautions, and meticulous environmental cleaning …

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